Keloidal pathophysiology: Current notions

Pathophysiology of Psoriasis: Current Concepts

The word ‘psoriasis’, is derived from the Greek word “psora” meaning “itch” or “scurf” or “rash”, although most patients suffering from the condition do not complain of itching. It has been known since ancient times and was originally considered a type of leprosy. For quite some time now, it is one of the most common human skin diseases. Up to a few deca‐ des back, psoriasis was considered to b...

Current concepts in the pathophysiology

Pathophysiology of sarcoidosis: current opinion

Pulmonary involvement is common in sarcoidosis, an immunemediated inflammatory disorder that is characterized by noncaseating granulomas in tissue. Sarcoid patients with advanced pulmonary disease, especially end-stage pulmonary fibrosis, risk developing pulmonary hypertension (World Health Organization group III pulmonary hypertension secondary to hypoxic lung disease). Increased levels of end...

Systemic sclerosis with keloidal nodules*

Nodular sclerosis is a rare form of presentation related to both systemic and localized forms of scleroderma. We describe the case of a patient with nodular sclerosis in order to alert the medical community to recognize this entity.

It Architecturing – Reconceptualizing Current Notions of Architecture in Is Reserach

The concept of architecture in relation to information systems research and practice is ambiguous and lacks a common agreed upon definition that combines the different areas of use. This paper investigates the origins of the concept and some of its common uses and conceptions. It is argued that the different conceptualizations of architecture are treated in an unreflectived manner and the effec...